Publication - Abstract
Aug 19, 2019
Molecular Pharmaceutics
C.B. Roces, S. Khadke, D. Christensen and Y. Perrie
Cationic liposomes prepared from dimethyldioctadecylammonium bromide (DDAB) and trehalose 6,6′-dibehenate (TDB) are strong liposomal adjuvants. As with many liposome formulations, within the laboratory DDAB:TDB is commonly prepared by the thin-film method, which is difficul...
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Publication - Summary
Nov 21, 2018
Blood
X. Ma, P. Zhou, A. Kugelmass, D. Toskic, M. Warner, L.X. Lee, T. Fogaren, M. Wang, Y. Li, L. Yang, Q. Xu and R. Comenzo
Researchers at Tufts University have recently reported a proof of concept for siRNA-LNP treatment for AL amyloidosis - a bone marrow disorder where Immunoglobulin (Ig) light chains (LC) misfold into amyloids that deposit in a variety of other tissues where they cause disfunction ...
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